Hypomethylation of tumor suppressor genes in odontogenic myxoma
نویسندگان
چکیده
منابع مشابه
Hypomethylation of tumor suppressor genes in odontogenic myxoma.
Odontogenic myxoma (OM) is an ectomesenchymal benign odontogenic tumor characterized by spindle or stellate-shaped cells embedded in an abundant myxoid or mucoid extracellular matrix. DNA methylation is characterized by the addition of methyl groups in cytosines within CpG islands in the promoter gene. DNA methylation can decrease the expression of tumor suppressor genes and contribute to the d...
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ژورنال
عنوان ژورنال: Brazilian Dental Journal
سال: 2011
ISSN: 0103-6440
DOI: 10.1590/s0103-64402011000500013